New Autism Research Clues
Studies of a Massachusetts town have attributed autism to congenital environmental causes. In some cases, autism may lead to the body's natural painkillers, called endorphins, to go too far in suppressing feeling. Probably several causes and etiological pathways lead to disorders in the autism spectrum. Most believe autism to have a multitude of probable causes. In the attempt to identify autism's causes, researchers had long sought to pinpoint precisely when the disorder begins. A peptide found in schizophrenia and autism instigates behavioral changes in rats. In fact, the only proven genetic causes of autism to date are well-defined syndromes like the Fragile X chromosome anomaly. Although researchers aren't sure just what signals the brain's wiring to go awry, reports imply that autism's roots lie in a person's genes. Over-emphasis on genetic aspects may not take enough account of several causes that are needed to explain the various types of autism. Even for the autism-spectrum disorders with known genetic causes, the molecular mechanism of pathology is not well comprehended. Genetic factors and brain abnormalities at birth are believed to be some of the most recognized causes of autism. Potential molecular causes of autism and other neurological disorders could be associated with mis-folding of proteins. NICHD researchers are looking into a variety of possible causes for both early onset and regressive autism. Some people with autism have mutations in the Pten gene, but it is unclear if that's what causes the disorder. Because autism itself and its causes are so mystifying, the international symbol for autism is a puzzle piece. It is typically accepted that autism is caused by abnormalities in brain structures.
Asperger Syndrome and Autism
Most recent thought among most stipulates that the causes of Asperger syndrome are the same as those of autism. Some disagree, arguing that Asperger syndrome and autism have different causes. Though autism's causes are murky, one fact about the syndrome is clear: it runs in families. Some people with autism, typically males, have fragile X syndrome, which leads to mental retardation.
Autism Disorder
Autism leads to impairments in communication, ability to learn, and social relatedness. It has turn out to be clear that genetic elements contribute significantly to the appearance of the disease. Autism, also referred as infantile autism or autistic disease, is a lifelong disorder that causes abnormal neurological development. The causes of autism are poorly comprehended, though it is clear that autism is a biological brain disorder.
Possible Causes of Autism
The causes of autism have long baffled investigators and frustrated parents. Theories in regards to prospective autism causes include genetics, environmental toxins, infections, and even vaccinations. Many additional hypotheses, such as the consumption of folic acid in pregnancy, have been proposed as likely causes of autism. Infection of pregnant woman with "wild" rubella virus is one of the few known causes of autism. A peptide found in schizophrenia and autism leads to behavioral changes in rats. There are other mechanisms of autism besides peptides, although maybe as much as 80% are peptide mediated. Congenital rubella, HIV, and herpes simplex have all been indicated as probable autism causes. While the causes of autism still continue a mystery, it has become obvious that genetic factors contribute prominently to the appearance of the disorder. Though autism's causes are hidden, one reality about the syndrome is clear: it runs in households.
The excellent news is that research is appearing to reveal autism's causes and signs, in particular evidence of a genetic link. This research reflects a shift in scientific thinking about what affects autism, and a drive to look harder at possible environmental influences. The Autism Research Center (www.autismresearchcentre.com) conducts research and disseminates results on the causes of autism and on methods of preventing, diagnosing and treating the disease. Research indicates that there may be several different autism causes. Autism is a neurological disorder that leads to impairments in communication, ability to learn, and social relatedness. Simply put, autism affects a kid to retreat into an inner universe. Little is known regarding the causes, treatment and prevention of autism. Because the main causes of autism in children are not greatly understood, targeted prevention is difficult. No one knows precisely what leads to Autism Spectrum Disorders (ASDs), but scientists think that both genetic and environmental factors may play a role. Until the mid 1990's, research into the causes of autism was limited to a few dedicated individuals who obtained little funding. During the 1990s, there has been a substantial push to promote research into the causes of autism. Amazingly, it took a good number of years for researchers to finally say without an uncertainty that cold parents are not one of the Autism causes. Patients, researchers and doctors from throughout the world have banded together to commence to crack the mystery of what leads to autism.
MMR vaccination
Current scientific evidence does not confirm that MMR vaccine, or any combination of vaccines, signals the development of autism, including regressive forms of autism. Anyhow, a small but vocal group of parents have taken to saying that thimerosal causes autism. If thimerosal causes autism, the prevalence of the disorder should have declined as the chemical was removed from vaccines. This is not supported by the realities. Current scientific evidence does not confirm that MMR vaccine, or any combination of vaccines, causes the development of autism, including regressive forms of autism. However, determination of whether MMR vaccination causes autism is best made by studying the incidence of autism in both vaccinated and un-vaccinated children. These studies provide little evidence to support a hypothesis that MMR vaccination leads to autism. Even if measles virus were consistently shown to be present in intestinal specimens of children, this would not conclusively indicate that measles causes autism. Therefore, these findings return evidence against the hypothesis that MMR vaccination causes autism. Many parents blame vaccines for the explosion in autism, which causes bizarre repetitive behavior and an inability to establish emotional ties. There is a theory out there that MMR vaccination with thimerosol causes autism in young children.
Autism Research
The happy news is that investigation is beginning to reveal autism's causes and signs, in particular evidence of a genetic link. For instance, there is a global research project aiming to pin down the genetic causes of autism by studying 6,000 DNA samples from families affected. NIH research on probable genetic, infectious, immunological, and environmental causes and mechanisms of autism carries on. Investigation into the causes of autism spectrum disorders is being fueled by recent research developments. The U.S. Health and Human Services (HHS) continues to support researching into the causes and treatments for autism spectrum disorders. The CDC is committed to protecting the well being of children and to identifying the biological and environmental causes of autism and supplementary developmental disabilities.
Conclusion
The popular theory now is that people can be born with a genetic predisposition that, coupled with specific environmental trigger, causes autism. Because the disorder is so complex, and because no two people with autism are precisely alike, autism is probably the result of multiple causes. Nothing will make the search for autism's causes simple. We don't know exactly what causes autism, but we do understand that both genes and environment are involved. There is no theory of the cause of autism which everybody has found convincing. However, parenting behaviors are not the trigger or a contributing factor to the cause or causes of autism.
